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Diagnostics
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Key diagnostic tests, when to take them, how they impact your fertility journey
Diagnostics are essential in fertility evaluation as they uncover the underlying causes of infertility, such as hormonal imbalances, structural abnormalities, or genetic factors, enabling targeted treatments. They prevent unnecessary interventions by ensuring accurate identification of issues affecting either partner, improving efficiency and outcomes.

By guiding personalized treatment plans, diagnostics optimize success rates in assisted reproductive techniques like IVF or IUI. Moreover, they help address comorbidities like thyroid dysfunction or diabetes that impact reproductive health.

Overall, diagnostics provide a comprehensive understanding of fertility challenges, empowering patients and clinicians to make informed decisions for effective family-building solutions.

Our aim is to guide users in understanding risk factors/symptoms for various infertility conditions and the recommended diagnostics tests.

Do right tests at the right time based on your "Risk Factors"

Ovulatory Disorders:

Irregular or absent ovulation affecting egg release, commonly linked to conditions like PCOS and thyroid imbalances.

  • Irregular or absent menstrual cycles (amenorrhea/oligomenorrhea)
  • Short or long cycles
  • Infertility with normal semen analysis
1) Hormonal Testing:
FSH (Day 3): Assesses ovarian reserve and ovulatory function.
LH: Evaluates ovulation timing and PCOS.
Prolactin: Identifies hyperprolactinemia.
TSH: Screens for thyroid dysfunction.
Estradiol: Indicates ovarian function.
Mid-Luteal Progesterone: Confirms ovulation.

2) Pelvic Ultrasound:
Assesses follicular development and ovarian morphology (e.g., PCOS).

3) Basal Body Temperature Charting:
Identifies ovulation timing.

Tubal Factor Infertility:

Blocked or damaged fallopian tubes prevent fertilization by hindering egg and sperm interaction.

  • History of pelvic infections (PID or STIs)
  • History of ectopic pregnancy
  • HSG suggests blocked fallopian tubes
Hysterosalpingography (HSG): Confirms tubal blockages or abnormalities.
Laparoscopy with Chromopertubation: Confirms tubal patency or detects pelvic adhesions.
Chlamydia Antibody Test: Suggests past pelvic infections.

Uterine Factor Infertility:

Structural issues or abnormalities in the uterus, such as fibroids or septa, impacting implantation and pregnancy.

  • Recurrent pregnancy loss
  • Heavy or irregular bleeding
  • History of uterine surgery or congenital anomalies
Hysteroscopy: Detects fibroids, polyps, or uterine scarring.
HSG: Confirms structural abnormalities (e.g., septate uterus).
3D Ultrasound or MRI: Confirms uterine anomalies or fibroids.
Endometrial Biopsy: Confirms chronic endometritis or endometrial receptivity issues.

Cervical Factor Infertility:

Cervical issues, including insufficient cervical mucus or anatomical problems, hindering sperm passage.

  • Pain during intercourse or cervical abnormalities
  • History of cervical surgery (e.g., LEEP, cone biopsy)
  • Recurrent pregnancy loss in the second trimester
Post-Coital Test (PCT): Confirms hostile cervical mucus or poor sperm-mucus interaction.
Cervical Length Measurement (Ultrasound): Confirms cervical insufficiency.
Cervical Cultures: Confirms infections affecting the cervix (e.g., STIs).

Male Factor Infertility:

Poor sperm quality, count, or motility caused by lifestyle factors, hormonal imbalances, obstructions in the reproductive tract or genetic conditions.

Abnormal semen analysis

History of testicular surgery, trauma, or infections

Erectile or ejaculatory dysfunction

Semen Analysis: Confirms oligospermia, azoospermia, or poor sperm motility/morphology.
FSH, LH, Testosterone: Confirms hormonal causes of infertility.
Scrotal Ultrasound: Confirms varicocele or testicular abnormalities.
Genetic Testing: Confirms chromosomal or Y-chromosome microdeletions.
STI Testing: Confirms infections affecting sperm health.

Endometriosis:

Growth of endometrial-like tissue outside the uterus, causing pain and infertility by affecting reproductive organs.

Severe dysmenorrhea or chronic pelvic pain

Pain during intercourse (dyspareunia)

Infertility with no other cause

Pelvic Ultrasound or MRI: Confirms endometriomas or adhesions.
Laparoscopy with Biopsy: Confirms presence of endometrial-like tissue outside the uterus.
CA-125 Test: Suggestive of endometriosis but non-specific.

Recurrent Pregnancy Loss:

Multiple consecutive miscarriages due to genetic, hormonal, or anatomical issues, requiring detailed evaluation.

Two or more consecutive pregnancy losses

History of late miscarriages or stillbirths

Karyotyping: Confirms chromosomal abnormalities in partners or products of conception.
HSG or Hysteroscopy: Confirms uterine abnormalities (e.g., septate uterus).
Antiphospholipid Antibody Testing: Confirms antiphospholipid syndrome (APS).
Thrombophilia Testing: Confirms inherited clotting disorders (e.g., Factor V Leiden).
TSH, Prolactin, and Mid-Luteal Progesterone: Detects hormonal causes.
TORCH Panel: Confirms infections affecting pregnancy.

Ovarian Reserve Decline:

Reduction in the number and quality of eggs, often related to age, genetics, or medical treatments.

Advanced maternal age (>35 years)

History of ovarian surgery or chemotherapy

Irregular or shortened menstrual cycles

Anti-Müllerian Hormone (AMH): Confirms diminished ovarian reserve.
Antral Follicle Count (AFC): Confirms low ovarian reserve.
FSH and Estradiol (Day 3): Confirms ovarian aging.
Genetic Testing (e.g., FMR1): Detects familial premature ovarian failure.